Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and molecular characterization of Mycobacterium tuberculosis isolates resistant to both isoniazid and ethambutol.

Antimicrobial agents and chemotherapy - 1 Jun 2005

Parsons Linda M, Salfinger Max, Clobridge Anne, Dormandy Jillian, Mirabello Lisa, Polletta Valerie L, Sanic Ahmet, Sinyavskiy Oleg, Larsen Susan C, Driscoll Jeffrey, Zickas Genet, Taber Harry W

Abstract excerpt

In performing radiometric susceptibility testing on over 2,000 patient isolates of Mycobacterium tuberculosis during the past 6 years, we found that resistance to 7.5 microg/ml ethambutol (EMB) occurred only in isolates that are also resistant to 0.4 microg/ml isoniazid (INH). Using 157 selected isolates in the present study, we performed radiometric and agar proportion susceptibility tests and DNA sequencing of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Catalase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

Share to Ethambutol

Share to Isoniazid

Share to Oligonucleotides

Share to Pentosyltransferases

Share to Tuberculosis, Multidrug-Resistant

Source

Open in PubMed Open full text

Identifiers

PMID: 15917515
DOI: 10.1128/AAC.49.6.2218-2225.2005
PMCID: PMC1140517

Genes

EMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and molecular characterization of Mycobacterium tuberculosis isolates resistant to both isoniazid and ethambutol.PMID 15917515Read ↗

Molecular characterization of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from the USASemantic proximity Read ↗

Frequency of mutational changes in the embB among the ethambutol-resistant strains of Mycobacterium tuberculosis in Iran.Semantic proximity Read ↗

Molecular characterization of isoniazid-resistant Mycobacterium tuberculosis isolates collected in Australia.Semantic proximity Read ↗

Phenotypic and genotypic characterization of drug-resistant Mycobacterium tuberculosis strains.Semantic proximity Read ↗

Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities.Semantic proximity Read ↗

Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations.Semantic proximity Read ↗

Frequency of embB codon 306 mutations in ethambutol-susceptible and -resistant clinical Mycobacterium tuberculosis isolates in Kuwait.Semantic proximity Read ↗

Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update.Semantic proximity Read ↗

Rapid detection of ethambutol-resistant Mycobacterium tuberculosis strains by PCR-RFLP targeting embB codons 306 and 497 and iniA codon 501 mutations.Semantic proximity Read ↗

Detection of katG and inhA mutations to guide isoniazid and ethionamide use for drug-resistant tuberculosis.Semantic proximity Read ↗

Prevalence and resistance spectrum of ahpC mutations in isoniazid-resistant Mycobacterium tuberculosis isolates.Semantic proximity Read ↗

Detection of multidrug resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.