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Article

The location of KIT and PDGFRA gene mutations in gastrointestinal stromal tumours is site and phenotype associated.

Journal of clinical pathology - 1 Jun 2005

Penzel R, Aulmann S, Moock M, Schwarzbach M, Rieker R J, Mechtersheimer G

Abstract excerpt

AIMS: To assess the relation between KIT and PDGFRA mutations and the site of origin, histological phenotype, and pathomorphologically determined risk assessment in gastrointestinal stromal tumours (GISTs). METHODS: A series of 83 clinicopathologically characterised GISTs from 79 patients was analysed for KIT and PDGFRA mutations by polymerase chain reaction amplification, single strand conformation polymorphism...

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Share to DNA, Neoplasm
Share to Gastrointestinal Stromal Tumors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intestinal Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

Share to Risk Assessment

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 15917417
DOI: 10.1136/jcp.2004.021766
PMCID: PMC1770686

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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