Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cholesterol is required for the polarized secretion of erythropoietin in Madin-Darby canine kidney cells.

Archives of biochemistry and biophysics - 15 Jun 2005

Maruyama Masato, Kishimoto Michiyuki, Ishida Kayo, Watanabe Yoshihiko, Nishikawa Makiya, Masuda Seiji, Sasaki Ryuzo, Takakura Yoshinobu

Abstract excerpt

It has already been reported that stably expressed exogenous human wild-type EPO (wtEPO) is preferentially secreted to the apical side and one of the three N-linked carbohydrate chains critically acts as an apical sorting determinant in Madin-Darby canine kidney (MDCK) cells. It has been suggested that lipid rafts are involved in the apical sorting of membrane and secretory proteins. To investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrifugation, Density Gradient
Share to Detergents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Erythropoietin

Share to Interferon-beta

Share to Membrane Microdomains

Share to Octoxynol

Share to Sucrose

Source

Identifiers

PMID: 15916748
DOI: 10.1016/j.abb.2005.04.005

Genes

EPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cholesterol is required for the polarized secretion of erythropoietin in Madin-Darby canine kidney cells.PMID 15916748Read ↗

Polarized traffic towards the cell surface: how to find the routeSemantic proximity Read ↗

N-glycans mediate apical recycling of the sialomucin endolyn in polarized MDCK cells.Semantic proximity Read ↗

Selective control of basolateral membrane protein polarity by cdc42.Semantic proximity Read ↗

Modulation of endocytic traffic in polarized Madin-Darby canine kidney cells by the small GTPase RhoA.Semantic proximity Read ↗

Absence of Direct Delivery for Single Transmembrane Apical Proteins or Their “Secretory” Forms in Polarized Hepatic CellsSemantic proximity Read ↗

Targeting of an apical endosomal protein to endosomes in Madin-Darby canine kidney cells requires two sorting motifs.Semantic proximity Read ↗

Establishment and characterization of a novel polarized MDCK epithelial cellular model for CFTR studies.Semantic proximity Read ↗

Plasma membrane protein sorting in polarized epithelial cells.Semantic proximity Read ↗

Basolateral sorting of transforming growth factor-alpha precursor in polarized epithelial cells: characterization of cytoplasmic domain determinants.Semantic proximity Read ↗

Differential detergent resistance of the apical and basolateral NPPases: relationship with polarized targeting.Semantic proximity Read ↗

The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized madin-darby canine kidney cells.Semantic proximity Read ↗

Polarisation, key to good localisation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.