Article
Polarisation, key to good localisation.
Biochimica et biophysica acta - 1 Aug 2006
van Beest Moniek, Robben Joris H, Savelkoul Paul J M, Hendriks Giel, Devonald Mark A J, Konings Irene B M, Lagendijk Anne K, Karet Fiona, Deen Peter M T
Abstract excerpt
Polarisation of cells is crucial for vectorial transport of ions and solutes. In literature, however, proteins specifically targeted to the apical or basolateral membrane are often studied in non-polarised cells. To investigate whether these data can be extrapolated to expression in polarised cells, we studied several membrane-specific proteins. In polarised MDCK cells, the Aquaporin-2 water channel resides in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
