Article
In vivo retroviral marking of antigen-specific B lymphocytes.
Seminars in immunology - 1 Feb 1992
Krall W J, Braun J
Abstract excerpt
A major obstacle in the study of B lymphocyte development subsequent to immunization has been the paucity of distinctive phenotypic markers which might permit the separation and scrutiny of a mature antigen-experienced or memory cell population. To address this issue, we have introduced a recombinant non-replicating retrovirus into antigen-reactive lymph nodes in vivo using the expression of a reporter gene to...
Topics
- Animals
- B-Lymphocyte Subsets
- Cell Movement
- Clone Cells
- Genetic Markers
- Genetic Vectors
- Immunization
- Immunologic Memory
- Lymph Nodes
- Mice
- Mice, Inbred CBA
- Phenotype