Article
In vivo retroviral marking of antigen-specific B lymphocytes.
Seminars in immunology - 1 Feb 1992
Krall W J, Braun J
Abstract excerpt
A major obstacle in the study of B lymphocyte development subsequent to immunization has been the paucity of distinctive phenotypic markers which might permit the separation and scrutiny of a mature antigen-experienced or memory cell population. To address this issue, we have introduced a recombinant non-replicating retrovirus into antigen-reactive lymph nodes in vivo using the expression of a reporter gene to...
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