Temperature gradient capillary electrophoresis (TGCE)--a tool for the high-throughput discovery and mapping of SNPs and IDPs.

doi:10.1007/s00122-005-1997-5

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Temperature gradient capillary electrophoresis (TGCE)--a tool for the high-throughput discovery and mapping of SNPs and IDPs.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Jul 2005

Hsia An-Ping, Wen Tsui-Jung, Chen Hsin D, Liu Zhaowei, Yandeau-Nelson Marna D, Wei Yanling, Guo Ling, Schnable Patrick S

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Temperature gradient capillary electrophoresis (TGCE) can be used to distinguish heteroduplex from homoduplex DNA molecules and can thus be applied to the detection of various types of DNA polymorphisms. Unlike most single nucleotide polymorphism (SNP) detection technologies, TGCE can be used even in the absence of prior knowledge of the sequences of the underlying polymorphisms. TGCE is both sensitive and...

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Temperature gradient capillary electrophoresis (TGCE)--a tool for the high-throughput discovery and mapping of SNPs and IDPs.

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