Article
SNP genotyping by heteroduplex analysis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Paniego Norma, Fusari Corina, Lia Verónica, Puebla Andrea
Abstract excerpt
Heteroduplex-based genotyping methods have proven to be technologically effective and economically efficient for low- to medium-range throughput single-nucleotide polymorphism (SNP) determination. In this chapter we describe two protocols that were successfully applied for SNP detection and haplotype analysis of candidate genes in association studies. The protocols involve (1) enzymatic mismatch cleavage with...
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