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Article

Genetic manipulation of yeast to identify genes involved in regulation of chemosensitivity.

Methods in molecular medicine - 1 Jan 2005

Beretta Giovanni L, Perego Paola

Abstract excerpt

Fission and budding yeast have been regarded as valuable tools for studying several cellular processes in eukaryotic cells and have been exploited as model systems for the identification of determinants of chemosensitivity. Indeed, yeast mutants of DNA repair and cell cycle checkpoint pathways exhibit increased sensitivity to selected antitumor drugs, thereby allowing us to establish the role of specific genes in...

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PMID: 15911983
DOI: 10.1385/1-59259-889-7:241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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