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Article

The contribution of the ABCG2 C421A polymorphism to cancer susceptibility: a meta-analysis of the current literature.

BMC cancer - 1 Sept 2012

Chen Pin, Zhao Lin, Zou Peng, Xu Haitao, Lu Ailin, Zhao Peng

Abstract excerpt

BACKGROUND: ABCG2, also known as BCRP, is a half ATP-binding cassette (ABC) transporter that localizes to plasma membranes. Recently, a number of studies have investigated the relationship between the C421A polymorphism in ABCG2 and cancer risk in multiple populations and various types of cancers; however, this relationship remains unclear. Therefore, we performed a meta-analysis to further explore this...

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Identifiers

PMID: 22937733
DOI: 10.1186/1471-2407-12-383
PMCID: PMC3488524

Genes

ABCG2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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