Article
[Association of ABCG2 gene C421A polymorphism and susceptibility of primary gout in Han Chinese males].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2011
Li Fa-gui, Chu Yi, Meng Dong-mei, Tong Ya-wen
Abstract excerpt
OBJECTIVE: To assess the association between a C421A single nucleotide polymorphism (SNP) in exon 5 of ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2) gene and susceptibility of primary gout in Han Chinese males. METHODS: For 200 male patients with primary gout and 235 controls, the genotype of C421A locus was analyzed by PCR and direct sequencing. Blood glucose, uric acid, total cholesterol,...
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