Article
Resistance mutations before and after tenofovir regimen failure in HIV-1 infected patients.
Journal of medical virology - 1 Jul 2005
Wirden Marc, Marcelin Anne Genevieve, Simon Anne, Kirstetter Myriam, Tubiana Roland, Valantin Marc-Antoine, Paris Luc, Bonmarchand Manuela, Conan Francoise, Kalkias Laurence, Katlama Christine, Calvez Vincent
Abstract excerpt
So far, no study has examined the real impact of tenofovir (TDF)-regimen failure taking into account all patients in a current clinical practice. The aim of this study was to compare the nucleoside reverse transcriptase inhibitors (NRTIs) mutation profiles observed before TDF initiation and after TDF-regimen failure. All patients with genotypic resistance tests performed in this context were selected from the...
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