Article
First line treatment response in patients with transmitted HIV drug resistance and well defined time point of HIV infection: updated results from the German HIV-1 seroconverter study.
PloS one - 1 Jan 2014
Zu Knyphausen Fabia, Scheufele Ramona, Kücherer Claudia, Jansen Klaus, Somogyi Sybille, Dupke Stephan, Jessen Heiko, Schürmann Dirk, Hamouda Osamah, Meixenberger Karolin, Bartmeyer Barbara
Abstract excerpt
BACKGROUND: Transmission of drug-resistant HIV-1 (TDR) can impair the virologic response to antiretroviral combination therapy. Aim of the study was to assess the impact of TDR on treatment success of resistance test-guided first-line therapy in the German HIV-1 Seroconverter Cohort for patients infected with HIV between 1996 and 2010. An update of the prevalence of TDR and trend over time was performed. METHODS:...
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