Article
Cytokine genotypes correlate with pain and radiologically defined joint damage in patients with juvenile rheumatoid arthritis.
Rheumatology (Oxford, England) - 1 Sept 2005
Oen K, Malleson P N, Cabral D A, Rosenberg A M, Petty R E, Nickerson P, Reed M
Abstract excerpt
OBJECTIVES: Single nucleotide polymorphisms (SNPs) in cytokine genes have been associated with risk of a number of autoimmune diseases. Moreover, some SNPs are associated with variations in rates of in vitro gene expression, and it is therefore possible that these functional polymorphisms may differentially affect inflammatory processes and disease outcome. This project's objective was to determine whether...
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