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Article

Genetics of serum concentration of IL-6 and TNFα in systemic lupus erythematosus and rheumatoid arthritis: a candidate gene analysis.

Clinical rheumatology - 1 Aug 2015

Solus Joseph F, Chung Cecilia P, Oeser Annette, Li Chun, Rho Young Hee, Bradley Kevin M, Kawai Vivian K, Smith Jeffrey R, Stein C Michael

Abstract excerpt

Elevated concentrations of inflammatory mediators are characteristic of autoimmune disease accompanied by chronic or recurrent inflammation. We examined the hypothesis that mediators of inflammation known to be elevated in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are associated with genetic polymorphism previously identified in studies of inflammatory disease. Serum interleukin 6 (IL-6)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25652333
DOI: 10.1007/s10067-015-2881-6
PMCID: PMC4526456

Genes

NOD2
CSF1
CSF2
PTPN2
TNFSF4
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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