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Article

Nuclear import and export signals in control of Nrf2.

The Journal of biological chemistry - 12 Aug 2005

Jain Abhinav K, Bloom David A, Jaiswal Anil K

Abstract excerpt

Nrf2 binds to the antioxidant response element and regulates expression and antioxidant induction of a battery of chemopreventive genes. In this study, we have identified nuclear import and export signals of Nrf2 and show that the nuclear import and export of Nrf2 is regulated by antioxidants. We demonstrate that Nrf2 contains a bipartite nuclear localization signal (NLS) and a leucine-rich nuclear export signal,...

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Identifiers

PMID: 15901726
DOI: 10.1074/jbc.M502083200

Genes

NES

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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