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Article

Genomewide screen for pulmonary function in 200 families ascertained for asthma.

American journal of respiratory and critical care medicine - 15 Aug 2005

Postma Dirkje S, Meyers Deborah A, Jongepier Hajo, Howard Timothy D, Koppelman Gerard H, Bleecker Eugene R

Abstract excerpt

Changes in pulmonary function are important in determining asthma outcome. Genetic factors may influence airway obstruction in asthma. We performed a genomewide screen in 200 families of probands objectively diagnosed with asthma in the 1960s to identify chromosomal regions related to changes in pre- and postbronchodilator lung function (FEV1, VC, and FEV1%VC) and assess influences of early-life smoke exposure....

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Identifiers

PMID: 15901612
DOI: 10.1164/rccm.200407-864OC
PMCID: PMC2718527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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