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Article

Genome-wide interrogation of longitudinal FEV1 in children with asthma.

American journal of respiratory and critical care medicine - 15 Sept 2014

Wu Kehua, Gamazon Eric R, Im Hae Kyung, Geeleher Paul, White Steven R, Solway Julian, Clemmer George L, Weiss Scott T, Tantisira Kelan G, Cox Nancy J, Ratain Mark J, Huang R Stephanie

Abstract excerpt

RATIONALE: Most genomic studies of lung function have used phenotypic data derived from a single time-point (e.g., presence/absence of disease) without considering the dynamic progression of a chronic disease. OBJECTIVES: To characterize lung function change over time in subjects with asthma and identify genetic contributors to a longitudinal phenotype. METHODS: We present a method that models longitudinal FEV1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25221879
DOI: 10.1164/rccm.201403-0460OC
PMCID: PMC4214107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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