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Article

Genetic linkage and association analysis of COPD-related traits on chromosome 8p.

COPD - 1 Dec 2006

Hersh Craig P, DeMeo Dawn L, Raby Benjamin A, Litonjua Augusto A, Sylvia Jody S, Sparrow David, Reilly John J, Silverman Edwin K

Abstract excerpt

Genome-wide linkage analysis in the Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study has demonstrated significant evidence of linkage to chromosome 8p for forced expiratory volume in 1 second, an important COPD-related phenotype. In this study, we sought to fine map the linkage peak and to test variants in two candidate genes for association with COPD and related traits. In a variance...

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Share to beta-Defensins
Share to Chromosomes, Human, Pair 8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forced Expiratory Volume

Share to Genetic Linkage

Share to Microsatellite Repeats

Share to Pulmonary Disease, Chronic Obstructive

Share to Quantitative Trait, Heritable

Share to Scavenger Receptors, Class A

Source

Identifiers

PMID: 17361499
DOI: 10.1080/15412550601009321

Genes

MSR1
DEFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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