Article
Promoter usage and alternative splicing.
Current opinion in cell biology - 1 Jun 2005
Kornblihtt Alberto R
Abstract excerpt
Recent findings justify a renewed interest in alternative splicing (AS): the process is more a rule than an exception as it affects the expression of 60% of human genes; it explains how a vast mammalian proteomic complexity is achieved with a limited number of genes; and mutations in AS regulatory sequences are a widespread source of human disease. AS regulation not only depends on the interaction of splicing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
