Article
The types and prevalence of alternative splice forms.
Current opinion in structural biology - 1 Jun 2006
Zavolan Mihaela, van Nimwegen Erik
Abstract excerpt
The finding that eukaryotic gene structures are extremely complex prompted the development of new experimental techniques for the accurate measurement of transcription start site usage and of the expression of alternative splice forms. On the computational side, analyses of large databases of splice variants revealed differences in the length, motif composition and selection pressure between constitutive and...
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