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Article

Alternative Splicing of Transcription Factors Genes in Muscle Physiology and Pathology

19 Feb 2018

Abstract excerpt

Skeletal muscle formation is a multi-step process that is governed by complex networks of transcription factors. The regulation of their functions is in turn multifaceted, including several mechanisms, among them alternative splicing (AS) plays a primary role. On the other hand, altered AS has a role in the pathogenesis of numerous muscular pathologies. Despite these premises, the causal role played by the...

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PMID: 29463057
DOI: 10.3390/genes9020107

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