Article
Association of IL-1Ra gene polymorphism, but no association of IL-1beta and IL-4 gene polymorphisms, with Kawasaki disease.
Journal of clinical laboratory analysis - 1 Jan 2005
Wu Shu-Fen, Chang Jeng-Sheng, Wan Lei, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
The purpose of this study was to evaluate whether IL-1 beta (IL-1beta promoter and IL-1beta exon 5), IL-1 receptor antagonist (IL-1 Ra), and IL-4 (IL-4 promoter and IL-4 intron 3) gene polymorphisms act as markers of susceptibility to Kawasaki disease (KD), or of the severity of the disease. The study included 107 KD patients and 103 normal controls. Polymorphisms for cytokine genes were detected by polymerase...
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