Article
Association of interleukin-1 alpha gene polymorphism with cerebral infarction.
Brain research. Molecular brain research - 4 Jul 2003
Um Jae-Young, Moon Kyung-Suk, Lee Kang-Min, Yun Jong-Min, Cho Kwang-Ho, Moon Byung-Soon, Kim Hyung-Min
Abstract excerpt
Interleukin-1 (IL-1) has pleiotropic actions in the central nervous system. During the last decade, a growing corpus of evidence has indicated an important role of this cytokine in the development of brain damage following cerebral ischemia. The expression of IL-1 in the brain is dramatically increased during the early and chronic stage of infarction. The IL-1 gene cluster on chromosome 2q14 contains three...
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