Article
Coding single-nucleotide polymorphisms of interleukin-1 gene cluster are not associated with Kawasaki disease in the Korean population.
Pediatric cardiology - 1 Apr 2011
Kim Su Kang, Kang Sung Wook, Chung Joo-Ho, Lee Jong Seok, Park Hyun Kyung, Yoon Kyung Lim, Kim Soo Cheol
Abstract excerpt
This study aimed to examine whether coding single-nucleotide polymorphisms (cSNPs) of the interleukin-1 gene cluster [interleukin-1-alpha (IL1α), IL1β, IL-1-receptor antagonist (IL1RN)] are genetic markers of susceptibility to Kawasaki disease (KD) in the Korean population. The study enrolled 109 KD patients and 287 healthy control subjects. Four cSNPs [rs17561 (Ala114Ser) of IL1α, rs1143634 (Phe105Phe) of IL1β,...
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