Article
Functional IFNG polymorphism in intron 1 in association with an increased risk to promote sporadic breast cancer.
Immunogenetics - 1 May 2005
Saha Anjana, Dhir Ashish, Ranjan Anand, Gupta Vibhuti, Bairwa Narendra, Bamezai Ramesh
Abstract excerpt
Interferon (IFN)-gamma is an important Th1 cytokine, which plays a role in immune surveillance and anti-tumor activity. A case-control study involving 54 sporadic breast cancer patients and 144 healthy controls was carried out to explore if the genotype variation of a proposed non-specific enhancer element with a dinucleotide (CA)n repeat in intron 1 has a role in the susceptibility to promote sporadic breast...
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