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Article

Lack of association between interferon gamma +874 T/A polymorphism and cancer risk: an updated meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014

Ge Yu-Zheng, Wang Yi-Dan, Xu Zheng, Xu Lu-Wei, Wang Ya-Ping, Gu Mao-Hong, Ding Ai-Xing, Zhu Xian-Bo, Wu Ran, Li Wen-Cheng, Xu You-Di, Jia Rui-Peng

Abstract excerpt

Interferon gamma (IFN-γ) is a potent proinflammatory cytokine which plays a pivotal role in the antiviral, antiproliferative, and antitumor activities. A T-to-A transition at the position +874 of human IFN-γ gene (IFNG) has been reported to influence the secretion of IFN-γ and affect cancer susceptibility. However, results from published studies on the association between IFNG +874 T/A polymorphism and cancer...

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PMID: 24671824
DOI: 10.1007/s13277-014-1861-9

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IFNG

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Lack of association between interferon gamma +874 T/A polymorphism and cancer risk: an updated meta-analysis.PMID 24671824Read ↗

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Interferon gamma +874 T/A polymorphism contributes to cancer susceptibility: a meta-analysis based on 17 case-control studies.Semantic proximity Read ↗

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