Article
IFN-γ+874 A/T polymorphism and cancer risk: an updated analysis based on 32 case-control studies.
Cytokine - 1 Nov 2011
Liu Fei, Li Bo, Wei Yong-Gang, Chen Xi, Ma Yu, Yan Lv-Nan, Wen Tian-Fu, Xu Ming-Qing, Wang Wen-Tao, Yang Jia-Yin
Abstract excerpt
IFN-γ is a T-helper 1 cytokine and plays important roles in modulating almost all the immune responses, such as hematopoiesis, T-cell differentiation, antiproliferative, antiviral, and antitumor activities. A single nucleotide polymorphism (+874A/T) which is located in the first intron of the human IFN-γ gene can putatively influence the secretion of IFN-γ. Results from previous studies on the association of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
