Article
Polymorphisms of the human IFNG gene noncoding regions.
Immunogenetics - 1 Jan 2000
Bream J H, Carrington M, O'Toole S, Dean M, Gerrard B, Shin H D, Kosack D, Modi W, Young H A, Smith M W
Abstract excerpt
Interferon gamma (IFN-gamma) is a multifunctional cytokine that is essential in the development of Th1 cells and in cellular responses to a variety of intracellular pathogens including human immunodeficiency virus (HIV-1). We screened genomic DNA samples from a predominately Caucasian male population of HIV-infected and healthy donors for polymorphisms in the human IFNG gene from -777 to +5608 by single-stranded...
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