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Article

Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: Biphasic influence of dose, age, gender, and receptor genotype.

Clinical pharmacology and therapeutics - 1 May 2005

King Danuta, Etzel Jason P, Chopra Shagun, Smith Joshua, Cadman Peter E, Rao Fangwen, Funk Stephen D, Rana Brinda K, Schork Nicholas J, Insel Paul A, O'Connor Daniel T

Abstract excerpt

BACKGROUND AND OBJECTIVES: Activation of alpha 2 -adrenergic receptors regulates a broad spectrum of physiologic responses, including blood pressure (centrally and peripherally), sedation, analgesia, insulin release, renal function, cognition, and behavior. The purpose of this study was to explore systematically the local vascular responses in humans triggered by a highly selective alpha 2 -adrenergic agonist...

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Share to Adrenergic alpha-Agonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, alpha-2

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Source

Identifiers

PMID: 15900285
DOI: 10.1016/j.clpt.2005.02.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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