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Article

Extracellular superoxide dismutase (EC-SOD) gene mutations screening in a sample of Mediterranean population.

Mutation research - 15 Oct 2005

Campo Salvatore, Sardo Adriana M, Campo Giuseppe M, D'Ascola Angela, Avenoso Angela, Castaldo Maria, Saitta Carlo, Lania Amalia, Saitta Antonino, Calatroni Alberto

Abstract excerpt

The main role of superoxide dismutases (SODs) is to eliminate reactive oxygen species in cells and tissues. Extracellular SOD (EC-SOD/SOD3) is a major superoxide scavenger and it is located on cell surfaces and primarily in extracellular matrix, and binds heparan sulfates by its carboxyterminal portion. Human EC-SOD gene is located on chromosome 4 and comprises three exons and two introns. The SOD3 coding...

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Source

Identifiers

PMID: 15899505
DOI: 10.1016/j.mrfmmm.2005.04.001

Genes

SOD3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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