Article
Association of extracellular superoxide dismutase (SOD3) Ala40Thr gene polymorphism with pre-eclampsia complicated by severe fetal growth restriction.
European journal of obstetrics, gynecology, and reproductive biology - 1 Feb 2009
Rosta Klára, Molvarec Attila, Enzsöly Anna, Nagy Bálint, Rónai Zsolt, Fekete Andrea, Sasvári-Székely Mária, Rigó János, Vér Agota
Abstract excerpt
OBJECTIVE: Placental and systemic oxidative stress with an imbalance in the oxidant/antioxidant activity seems to play a central role in the pathogenesis of pre-eclampsia. The aim of our study was to examine whether two missense polymorphisms of the extracellular superoxide dismutase (SOD3) gene (Arg213Gly and Ala40Thr) are associated with pre-eclampsia in a Caucasian population from Hungary. STUDY DESIGN: One...
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