Article
Polymorphic variants of extracellular superoxide dismutase gene in a Romanian population with atheroma.
Biochemical genetics - 1 Oct 2008
Samoila Olguta C, Carter Angela M, Futers Simon T, Otiman Gabriela, Anghel Andrei, Tamas Liviu, Seclaman Edward
Abstract excerpt
Extracellular superoxide dismutase (EC-SOD) is the main SOD isoform in the arterial wall contributing to cardiovascular defense against oxidative stress by removing the superoxide anion. In our study, the Thr40Ala and Arg213Gly polymorphic variants of the EC-SOD gene (SOD ( 3 )) were investigated for associations with atherosclerosis and other related factors in 144 subjects with significant atheroma (having one,...
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