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Article

Paraoxonase-1 activity modulates endothelial function in patients with peripheral arterial disease.

Atherosclerosis - 1 Dec 2005

Pasqualini Leonella, Cortese Claudio, Marchesi Simona, Siepi Donatella, Pirro Matteo, Vaudo Gaetano, Liberatoscioli Laura, Gnasso Agostino, Schillaci Giuseppe, Mannarino Elmo

Abstract excerpt

Human serum paraoxonase-1 (PON1) is thought to play a role in the favorable vascular effects of high-density lipoproteins, mainly through a reduction in low-density lipoprotein oxidation. Endothelial dysfunction, characterized by an impaired capacity of the arteries to dilate in response to a num...

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Source

Identifiers

PMID: 15899485
DOI: 10.1016/j.atherosclerosis.2005.03.030

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15899485-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Paraoxonase-1 activity modulates endothelial function in patients with peripheral arterial disease.PMID 15899485Read ↗

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