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Article

Association study of four activity SNPs of CYP3A4 with the precocious puberty in Chinese girls.

Neuroscience letters - 24 Jun 2005

Xin Xiujuan, Luan Xiaohui, Xiao Junhua, Wei Dongzhi, Wang Jianhui, Lu Daru, Yang Shengli

Abstract excerpt

CYP3A4 plays an important role in the metabolism of a variety of endogenous and exogenous compounds. Earlier studies revealed that a high-activity variation of the CYP3A4 gene, CYP3A4*1B is significantly associated with the precocious puberty in girls. Other three variations, CYP3A4*4, CYP3A4*5 and CYP3A4*6, which were found in a study carried out in a Chinese population in Taiwan, were reported to down-regulate...

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Identifiers

PMID: 15896485
DOI: 10.1016/j.neulet.2005.02.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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