Article
Association study in Taiwanese girls with precocious puberty.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2011
Chou I-Ching, Wang Chung-Hsing, Lin Wei-De, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: The timing of puberty has a genetic component. Recently, genome-wide association studies have identified that rs314280 on 6q21 (near the LIN28B gene) and rs2090409 on 9q31.2 (in an intergenic region) are associated with age at menarche. In this study, we aimed to determine whether the two loci were associated with the timing of puberty in Taiwanese girls. RESULTS: A total of 117 girls were divided...
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