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Article

Association of obesity and menarche SNPs and interaction with environmental factors on precocious puberty.

Pediatric research - 1 Sept 2024

Xue Peng, Lin Jianfei, Tang Jingyi, Chen Yao, Yu Tingting, Chen Chang, Kong Huijun, Lin Cuilan, Liu Shijian

Abstract excerpt

BACKGROUND: Obesity is an important cause for the precocious or early puberty. However, the association between obesity-related loci and the risk of precocious puberty as well as the effect of gene-environment interaction are unclear, especially in the Chinese children population. METHODS: This was a case-control study using baseline data from two cohorts and hospital cases in China. 15 SNPs loci and several...

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PMID: 38649724
DOI: 10.1038/s41390-024-03168-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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