Article
Obesity-related genetic polymorphisms are associated with the risk of early puberty in Han Chinese girls.
Clinical endocrinology - 1 Mar 2022
Li Di, Zhang Boxian, Cheng Jinquan, Chen Dingyan, Wu Yu, Luo Qingshan, Zhou Li
Abstract excerpt
OBJECTIVE: To explore the association between obesity and precocious puberty from the perspective of genetic polymorphism. DESIGN: Two hundred and ninety-eight pairs of girls in early puberty and age-matched controls (±3 months) were recruited. The genotypes of four obesity-related single-nucleotide polymorphism (SNP) loci (rs10968576, rs12935153, rs4674340 and rs7635103) were determined and the effect of...
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