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Article

The role of cysteine residues in the sulphate transporter, SHST1: construction of a functional cysteine-less transporter.

Biochimica et biophysica acta - 20 May 2005

Howitt Susan M

Abstract excerpt

We investigated the role of cysteine residues in the sulphate transporter, SHST1, with the aim of generating a functional cysteine-less variant. SHST1 contains five cysteine residues and none was essential for function. However, replacement of C421 resulted in a reduction in transport activity. Sulphate transport by C205 mutants was dependent on the size of the residue at this position. Alanine at position 205...

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PMID: 15893511
DOI: 10.1016/j.bbamem.2005.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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