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Article

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency.

Cell - 28 Jul 1995

Schmidt B, Selmer T, Ingendoh A, von Figura K

Abstract excerpt

Multiple sulfatase deficiency (MSD) is a lysosomal storage disorder characterized by a decreased activity of all known sulfatases. The deficiency of sulfatases was proposed to result from the lack of a co- or posttranslational modification that is common to all sulfatases and required for their catalytic activity. Structural analysis of two catalytically active sulfatases revealed that a cysteine residue that is...

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Identifiers

PMID: 7628016
DOI: 10.1016/0092-8674(95)90314-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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