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Article

Residues in the pathway through a membrane transporter.

Proceedings of the National Academy of Sciences of the United States of America - 20 Jun 1995

Yan R T, Maloney P C

Abstract excerpt

The structure of solute transporters is understood largely from analysis of their amino acid sequences, and more direct information is greatly needed. Here we report work that applies cysteine scanning mutagenesis to describe structure-function relations in UhpT, a bacterial membrane transporter. By using an impermeant SH-reactive agent to probe single-cysteine variants, we show that UhpT transmembrane segment 7...

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Identifiers

PMID: 7597063
DOI: 10.1073/pnas.92.13.5973
PMCID: PMC41624

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Source receipt: pubmed, retrieved 7 Sept 2026.

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