Article
Characterization of a ribonuclease gene and encoded protein from the reptile, Iguana iguana.
Gene - 6 Jun 2005
Nitto Takeaki, Lin Cynthia, Dyer Kimberly D, Wagner Robert A, Rosenberg Helene F
Abstract excerpt
In this work we identify an intronless open reading frame encoding an RNase A ribonuclease from genomic DNA from the Iguana iguana IgH2 cell line. The iguana RNase is expressed primarily in pancreas, and represents the majority of the specific enzymatic activity in this tissue. The encoded sequence shares many features with its better-known mammalian counterparts including the crucial His12, Lys40 and His114...
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