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Article

Expression of IgM, IgD, and IgY in a Reptile, <i>Anolis carolinensis</i>

28 Aug 2009

Abstract excerpt

The reptiles are the last major group of jawed vertebrates in which the organization of the IGH locus and its encoded Ig H chain isotypes have not been well characterized. In this study, we show that the green anole lizard (Anolis carolinensis) expresses three Ig H chain isotypes (IgM, IgD, and IgY) but no IgA. The presence of the delta gene in the lizard demonstrates an evolutionary continuity of IgD from fishes...

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PMID: 19717516
DOI: 10.4049/jimmunol.0803251

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