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Genome-Wide Analysis of Chromosomal Features Repressing Human Immunodeficiency Virus Transcription

12 May 2005

Abstract excerpt

We have investigated regulatory sequences in noncoding human DNA that are associated with repression of an integrated human immunodeficiency virus type 1 (HIV-1) promoter. HIV-1 integration results in the formation of precise and homogeneous junctions between viral and host DNA, but integration takes place at many locations. Thus, the variation in HIV-1 gene expression at different integration sites reports the...

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PMID: 15890899
DOI: 10.1128/jvi.79.11.6610-6619.2005

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