Advancements in single-cell techniques for examining the HIV reservoir: pathways to a cure

Abstract excerpt

T cells and other long-lived cells like macrophages. These reservoir cells, which persist despite suppressive antiretroviral therapy (ART), are thought to be influenced by several key factors such as position and orientation of chromosomal proviral integration, proviral intactness, and antigen specificity. The host's immune status and immune selection pressures also likely play a significant role. Recent data...

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