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Article

Synapsis and meiotic recombination analyses: MLH1 focus in the XY pair as an indicator

12 May 2005

Abstract excerpt

BACKGROUND: Anomalies in meiotic prophase I have been related to partial or total meiotic arrest. These anomalies include an abnormal synaptic process, resulting in disorders in meiotic recombination. METHODS: In the present study, we analyse primary spermatocytes from 12 infertile men (four with non-obstructive azoospermia, six with oligoastenoteratozoospermia, one with astenoteratozoospermia and one...

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PMID: 15890739
DOI: 10.1093/humrep/dei023

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