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Article

An azoospermic man with a double-strand DNA break-processing deficiency in the spermatocyte nuclei: case report.

Human reproduction (Oxford, England) - 1 May 2006

Sciurano R B, Rahn M I, Pigozzi M I, Olmedo S Brugo, Solari Alberto J

Abstract excerpt

BACKGROUND: The mechanisms of meiotic arrest in human spermatogenesis are poorly known. METHODS AND RESULTS: A testicular biopsy from an azoospermic male showed complete spermatogenesis arrest at the spermatocyte stage, asynapsis, lack of formation of the XY body, partial reversion to a mitotic-like division and cell degeneration both at the prophase and at the abnormal cell divisions. Synaptonemal complex...

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Source

Identifiers

PMID: 16495306
DOI: 10.1093/humrep/dei479

Genes

BRCA1
MLH1
RAD51
SYCP1
SYCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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