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Article

Meiotic non-disjunction mechanisms in human fertile males

1 Mar 2012

Abstract excerpt

BACKGROUND: In humans, little is known about the mechanisms of non-disjunction working in male meiosis, although considerable attention has been given to these mechanisms in female meiosis. The present study explores the origin of meiotic non-disjunction during human spermatogenesis and the chromosomes most commonly involved in this process. METHODS: We used Multiplex fluorescence in situ hybridization to carry...

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PMID: 22381620
DOI: 10.1093/humrep/des051

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