Article
Analysis of non-crossover bivalents in pachytene cells from 10 normal men.
Human reproduction (Oxford, England) - 1 Sept 2006
Sun Fei, Oliver-Bonet M, Liehr T, Starke H, Turek P, Ko E, Rademaker A, Martin R H
Abstract excerpt
BACKGROUND: Bivalents with no recombination foci (possible achiasmates) are unable to orient properly on the metaphase plate or to segregate chromosomes to daughter cells. Non-crossover bivalents are known to cause meiotic arrest in various organisms. METHODS: Individual non-crossover bivalents were identified in 886 pachytene cells (19 492 bivalents) from testicular biopsies of 10 normal men. Fluorescence...
Topics
- Aged
- Aged, 80 and over
- Aneuploidy
- Biopsy
- Chromosomes, Human, Pair 21
- Chromosomes, Human, Pair 22
- Crossing Over, Genetic
- DNA Mutational Analysis
- DNA Repair
- Humans
- In Situ Hybridization, Fluorescence
- Karyotyping
- Male
- Middle Aged
