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Article

Premature separation of sister chromatids in human male meiosis

31 Jan 2008

Abstract excerpt

BACKGROUND: Meiotic disorders result in meiotic arrest and aneuploid spermatozoa, leading to male infertility, spontaneous abortions or affected offspring. We carried out meiotic studies in an infertile male to detect meiotic nondisjunction mechanisms leading to aneuploidy in spermatogenesis. METHODS AND RESULTS: Meiotic studies were performed in testicular and semen samples from a 38-year-old teratozoospermic...

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PMID: 18270181
DOI: 10.1093/humrep/dem427

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