Article
Synaptic defects at meiosis I and non-obstructive azoospermia.
Human reproduction (Oxford, England) - 1 Dec 2006
Topping Daniel, Brown Petrice, Judis LuAnn, Schwartz Stuart, Seftel Allen, Thomas Anthony, Hassold Terry
Abstract excerpt
BACKGROUND: Recent advances in immunofluorescence methodology have made it possible to directly monitor protein localization patterns in germ cells undergoing meiosis. We used this technology to examine the early stages of meiosis in testicular material obtained from men presenting for evaluation at infertility clinics. METHODS: Specifically, we compared meiotic progression, synapsis and recombination in 34...
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